Wireframe Ventures is a San Francisco-based venture capital firm founded in 2016, specializing in early-stage (seed and pre-seed) technology companies. The firm focuses on investments that aim to create a healthier and more sustainable future, with a particular emphasis on climate technology, biotechnology, and healthcare sectors. Their investment thesis integrates AI and automation to enhance solutions addressing critical global challenges. Wireframe Ventures typically provides initial checks ranging from $500,000 to $2 million, often leading or co-leading rounds, and is committed to supporting founders from inception through successful Series A institutional financing. The firm also prioritizes diversity and inclusion, with a significant portion of its portfolio companies led by first-time founders and underrepresented minority entrepreneurs.